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4-Octyl itaconate restricts STING activation by blocking its palmitoylation

This can be viewed as a form of homeostatic plasticity, where the CAS enhances its activity to maintain a relatively constant level of neural firing in response to diminished peripheral sensory input

Urolithin a protects against hypoxia-induced pulmonary hypertension by inhibiting pulmonary arterial smooth muscle cell pyroptosis via AMPK/NF-kB/NLRP3 signaling