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Name: depression and acetyl-l-carnitine Frontiers Do low levels of acetyl-L-carnitine
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Key pathways such as PI3K/AKT/mTOR (PAM), RAS/RAF/MEK/ERK [22], and Notch are frequently activated in GBM, promoting cell proliferation, survival, and invasion, while also contributing to the resistance of GBM cells to chemotherapy and radiation therapy