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This represents a substantial loss of recoverable energy and a significant source of greenhouse gas emissions, given methanes global warming potential

PMID 24780897

For researchers interested in the comparison between tirzepatide and next-generation compounds like retatrutide, which adds a third receptor (GCG), our guide to retatrutide versus semaglutide provides useful context, as does our three-way comparison of semaglutide, tirzepatide, and retatrutide