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TABLE 1 Summary of genes and signaling pathways that play an important role in intervertebral disc development

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Given the known role of glutamate-triggered calcium signaling in shaping the BG cell fate in mice, we used ionotropic glutamate receptor (NMDA versus non-NMDA type) antagonists to study the involvement of glutamate signaling in the regulation of the BG fate of NG2+ progenitors, and found that NMDA-type glutamate receptors play a role in the normal development of BG

The coupons analyzed during the experiment are located at 45 C looking from the center of the cylinder, although some of the coupons are placed +45 C (Supplementary Fig