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Glushakov, University of Virginia, United States Luz Navarro, National Autonomous University of Mexico, Mexico Updates Copyright 2024 Wu, Song, Teng, Li, Liu, Ma, Zhang, Zhang and Chen

The reaction is catalyzed by a family of enzymes called Glutathione S-transferases (GSTs), which facilitate a nucleophilic attack, covalently binding the sulfur atom of glutathione directly to the toxic Phase I metabolite

At 72 hours, all cell lines displayed a significant decrease ( p 1 or 15%, monitored daily), debilitating diarrhea, rough hair coat, hunched posture, labored breathing, lethargy, persistent recumbence, significantly abnormal neurological signs, bleeding from any orifice, self-induced trauma, impaired mobility, moribund, or otherwise unable to obtain food or water

TABLE 2 Relationship between microplastic characteristics and neurotoxic effects