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doi: 10.3389/fnut.2025.1754492 Received 26 November 2025 Revised 20 December 2025 Accepted 24 December 2025 Published 21 January 2026 Volume 12 - 2025 Edited by Javier Diaz-Castro, University of Granada, Spain Reviewed by Mahsa Rezazadegan, Isfahan University of Medical Sciences, Iran Soroush Taherkhani, Iran University of Medical Sciences, Iran Updates Copyright 2026 Poon, Li, Schweitzer and Akefe

It is uncommon for a hypothyroidism patient to be prescribed T3-only treatment without T4

Some helpful quick tips to follow to do so include: Maintain a healthy environment clear of exposure to heavy metals or molds Take precautions to reduce or eliminate most life stressors Eat whole, natural and organic foods rich in folate and methionine Supplement with the proper B vitamins Know your MTHFR gene status Test your homocysteine levels You can improve and excitingly, reverse epigenetic tags that cause your genes to function differently

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