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Glutathione (GSH), a ubiquitous tripeptide, also chelates Cu and facilitates Cu uptake and trafficking in animals, while its role in plants is mainly associated with detoxification of excessive Cu concentrations (Burkhead et al., Reference Burkhead, Gogolin Reynolds, Abdel-Ghany, Cohu and Pilon2009

Bridging that translational gulf demands a sharper focus on three interlocking realities: cost-effectiveness, real-world scalability, and sustained patient adherence