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University of Tennessee Medical Center

In this context, the added metabolic stress of high GH levels is much more likely to tip the scales and exacerbate the underlying problem

Additionally, GSH or GSSG are potential candidate ligands of NMDA receptors (NMDARs) because the constituent amino acid sequence bears a close structural resemblance to those of NMDAR activators 59

4.1.5 Paraoxonase 1 Paraoxonase 1 (PON1) is a calcium-dependent esterase primarily associated with high-density lipoprotein (HDL), where it plays a crucial role in reducing OS by hydrolyzing lipid peroxides and preventing low-density lipoprotein (LDL) oxidation (Figure 4)