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They play a crucial role in the processes of vesicle biogenesis and exocytosis, including membrane transport proteins (such as Rab GTPases), heat shock proteins (such as HSP70 and HSP90), and ESCRT-related proteins (such as Tsg101 and Alix) [71] (Fig

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Investigations of the Connectivity Map and high-throughput transcriptional profiling suggested that GHK (and by extension GHK-Cu) may up- or down-regulate thousands of genes, many of which are associated with tissue regeneration, extracellular matrix biology, inflammation, and oxidative stress response