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An operation is advisable for the following situations: Emergency Abscess inside the abdomen or pelvis that cannot be drained or suctioned with a tube by a radiologist Perforation with peritonitis (diffuse abdominal pain due to pus or feces spillage inside the abdomen, high fever, and distention) Persistent or worsening symptoms that do not respond to intravenous antibiotics Non-emergency Fistula to the bladder or vagina Multiple episodes of diverticulitis (typically three or more) Narrowing of the colon (stricture) causing obstruction Suspicion for a mass or cancer in cases with incomplete colonoscopy Weakened immune system such as in patients with immunodeficiency, transplant, or those receiving immunosuppression for medical conditions