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Shen Z, Wu W, Hazen SL: Activated leukocytes oxidatively damage DNA, RNA, and the nucleotide pool through halide-dependent formation of hydroxyl radical

In summary, we expected to see the occurrence of fibrosis in all four models in response to physiological and pathological stimulation, as well as tissue remodeling/repair and inflammation during subsequent wound healing, but the four IC/BPS models showed few similarities in their histopathological patterns