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On the other hand, endoplasmic reticulum stress can promote cell ferroptosis and may be involved in the co-regulation of ferroptosis and apoptosis [61]

Introduction: A Breakthrough in Metabolic Modulation

K.ByunY.ParkJ

In vitro studies using normal human epidermal keratinocytes revealed that treatment with glutathione amino acid precursors significantly increased both GSH and glutathione disulfide levels, leading to an improved GSH/glutathione disulfide ratio, which is a key indicator of cellular redox balance