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Statements Author contributions XZ: Data curation, Software, Visualization, Writing original draft

Compared to the water-treated control, callose deposition was increased by 1.07-fold in SA treated plants, 1.11-fold in MSNs-ss-OH treated plants, and 1.18-fold in MSNs-ss-OH and SA treated plants

Keywords: glutathione, meta-analysis, randomized controlled trial, Parkinson's disease Introduction Parkinson's disease (PD) is a progressive neurodegenerative disease associated with aging, which is characterized by the selective loss of nigrostriatal dopaminergic neurons (1-3)