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Validate key regulators (e.g., cell type-specific lncRNAs and lipid metabolic enzymes) using kidney organoid models, particularly patient-derived organoids (PDOs) that recapitulate disease-specific phenotypes (e.g., diabetic nephropathy and focal segmental glomerulosclerosis)

In vitro , in a colon epithelial cell line (Caco-2), TNF-induced increases in TJ permeability were associated with increased nuclear factor kappa beta (NF-B) activation and nuclear translocation of NF-B p65 [13]

E., Park, O., Park, T

Crohns Disease and Other GI Conditions B12 is absorbed in the terminal ileum (the last section of the small intestine)