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Mg 2+ removal from media can also be used to model seizure-like activity in neuronal cultures

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Figure 8 Finally, we confirmed that the use of iron chelators and ROS scavengers, such as thiourea, significantly reduced gentamicin-mediated mortality, which supports the hypothesis that the enhancement of the bactericidal action of gentamicin by cystine is mediated through the disruption of intracellular redox homeostasis