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Description

AMPK activation inhibits expression of proinflammatory mediators through downregulation of PI3K/p38 MAPK and NF-B signaling in murine macrophages

The process is irreversible and is controlled by the activity of two enzymes: cystathionine beta-synthase (CBS) and cystathionine gamma-lyase, both of which require the active form of vitamin B6, pyridoxal 5-phosphate, to function