[185] found that female rats exposed to NaF showed decreased serum levels of E2 and P4, along with reduced expression of FSHR, while estrogen receptor alpha (ER), progesterone receptor (PgR), and LHR expressions increased [185]
2297-C DEVELOPMENT OF A NOVEL IN VITRO MITOCHONDRIAL TOXICITY TEST BASED ON ATP INHIBITION SUBSTRATE ASSAY Hyunwoo Oh 1 , Hyo Young Lee 1 , Eileen Yoon 2 , Huiyul Park 3 , Sang Bong Ahn 4 , Joo Hyun Sohn 2 and Dae Won Jun 2 , (1)Uijeongbu Eulji Medical Center, (2)Hanyang University College of Medicine, (3)Hanyang University, (4)Eulji Medical Center Background: Mitochondrial toxicity has led to the withdrawal of numerous drugs from the market, highlighting the importance of assessing mitochondrial dysfunction during drug development
Nanoformulation of PROteolysis Targeting Chimera TArgeting Undruggable c-Myc for the treatment of pancreatic cancer
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