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Following performance testing of spls models (perf method of mixOmics package), we applied a feature stability filter and only kept features that achieved a minimum stability of 80% on the resulting sPLS models

Correspondingly, activating ABCA1-dependent reduction of membrane cholesterol by LXRs has been shown to modulate membrane lipid organization and preventing the localization of TLR4 adaptor molecules to lipid rafts, thereby impairing downstream MAPK and NFB signaling (38, 39)