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Receptor for advanced glycation endproducts (RAGE) is a key regulator of oval cell activation and inflammation-associated liver carcinogenesis in mice

There can be adverse effects when taking excess Lithium

The pathological relevance of defective mitophagy is illustrated by evidence that Pink1-deficient mice are protected from CS-induced emphysema [152], and that decreased Parkin levels in skeletal muscle contribute to muscle wasting in COPD patients [153]