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While we aimed to minimize confounding factors affecting metabolites, caution is needed when interpreting AA changes in SLE and LN patients, as factors like diet and inflammation may also influence metabolic pathways

Both fatty acyl tails are integral to ferroptosis (27)

Here, we found for the first time that GPX2 was upregulated in EGFR-TKI resistant NSCLC cells and tissues, accelerating the elimination of ROS and conferring drug resistance in NSCLC