l-glutathione and pregnancy Compounded Glutathione Injection Glutathione While Pregnant: Safety and

doi: 10.1111/jfpp.15101 43 MalbaaR.LonarE.DjuriM

doi: 10.3390/cells8121522 55 van de DonkNWCJ

Although oral therapy with the least toxic of these compounds, glutathione monoethyl ester, did raise erythrocyte and white blood cell glutathione levels in a few affected patients (W Rhead, unpublished results), it also provoked moderate gastrointestinal irritation resulting in vomiting and diarrhea, largely precluding oral therapy with this compound or other related molecules containing free sulfhydryls

While the association was modest, the findings were significant enough that the FDA felt it necessary to issue a news release in 2010 warning of the possible increased fracture risk (16)