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Figure 3: Dynamics of motor activity of the control (1) and Vilon-treated (2) test subjects in an open field as it relates to age, estimated by (a) number of crossed squares, (b) number of rearings, and (c) time of grooming When examining vaginal smear samples, the findings indicated that the overall duration of the estrous cycle in control mice increased with age while the relative number of short estrous cycles decreased, and the number of long cycles increased

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The comparison illustrates the difference between extensive clinical validation and promising but unvalidated preclinical data