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Wogonoside seems to alleviate colitis by protecting against intestinal barrier dysfunction through the reinforcement of tight junctions via regulation of the MLCK/pMLC2 signaling pathway in Caco2 cells [105], whereas in DSS-induced UC mice this compound seemed to lead to dual inhibition of NF-B and NLRP3 inflammasome [106]

doi: 10.1084/jem.20131916 158 BeuryDWCarterKANelsonCSinhaPHansonENyandjoMet al

Citation24 Larger particles (around 200 nm) exhibit higher piezoelectric catalytic activity but are easily phagocytosed by macrophages and have difficulties accumulating within tumor tissues