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KO has been proven to have anti-inflammatory properties

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Later, in 1946, Prof

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S., Idres, S

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PNS treatment was able to inhibit PI3K/Akt activation, increase IL-10 expression, significantly reduce the percentage of CD11BF4/80-labeled macrophages in DSS-induced SD rat colon tissue, and induced macrophage polarization to anti-inflammatory CD206 + M2 macrophages, thereby suppressing the intestinal inflammatory response (Lu et al., 2020)

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