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Essential elements include HPLC (High Performance Liquid Chromatography) purity testing showing 98% or higher purity, mass spectrometry confirming correct molecular identity, and endotoxin testing ensuring bacterial contamination remains within safe limits

If a product page talks about ergothioneine, capsules, or "the longevity vitamin," you are looking at the supplement

Evidence Boundary Most studied route in the Phase 2 program, but the OPTIONS trial missed its primary weight-loss endpoint and development was terminated in 2007

Reference: Dimet-Wiley AL, Latham CM, Brightwell CR, Neelakantan H, Keeble AR, Thomas NT, Noehren H, Fry CS, Watowich SJ (2024)