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Older and more recent works have shown that the peptide affects parameters related to NO generation and can modulate the response of tissues exposed to the presence of inhibitors or precursors of the nitric oxide pathway

[6] The TPSAB1 has also been implicated in pruritus, unexplained, gastrointestinal symptoms, and in other diseases including the recently discovered Hereditary Alpha Tryptasemia

Prolonged oxidative stress and delayed tissue repair exacerbate acetaminophen-induced liver injury in aged mice