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Nat Med 2015

L-Arginine Feature L-Arginine L-Carnitine Main Action Boosts nitric oxide, improves blood flow(by vasodilation) Supports energy and blood flow, helps NO indirectly Best For Mild ED, first natural step Poor response to ED meds, vascular/metabolic ED Typical Dose 2.56 g/day 2,000 mg/day (propionyl/acetyl) Adverse effects Generally safe Generally safe Citrulline supplements vs L-arginine Feature L-Arginine L-Citrulline Supplements How it works Direct NO precursor Converts to L-arginine, then NO Typical Dose 1,5006,000 mg/day 1,500 mg/day (studied) Side Effects GI discomfort, diarrhea (at high doses) Well-tolerated Best Use Mild-moderate ED Mild ED, or if L-arginine is ineffective L-Arginine vs

It is also important to note that LAC levels are decreased in obese subjects [63], emphasizing the need for future studies aimed at exploring a possible link between LAC metabolism and obesity in subjects with MDD

(2007) 8:R19