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Without vitamin C, collagen molecules are inadequately cross linked, resulting in weak tissue

Interestingly, in patients treated with bDMARDs, zonulin levels were lower than in those receiving conventional treatments ( p = 0.05)

Front Endocrinol (Lausanne) (2019) 10:811

TMX2 TMX2, which is localized in the MAM compartment, acts as an important sensor of redox conditions and is crucial for the maintenance of cellular redox homeostasis (Vandervore et al., 2019)