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Hudson & Tabet 2003 Cochrane Review: A Cochrane Review of 15 clinical trials (including 13 of those in the meta-analysis above) assessed 1 to 3 g/day ALCAR supplementation versus placebo over 12 to 52 weeks in participants with mild to moderate dementia or cognitive decline

Notably, heterozygosity in the ONT system was defined by a minor allele frequency (MAF) threshold above 0.60, highlighting the necessity of clinical validation for in-house designed ONT panels through comparison with second-generation NGS platforms

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Carnitine: An Osmolyte That Plays a Metabolic Role