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In monotherapy trials with semaglutide oral tablets for T2DM, severe hypoglycemia (requiring the assistance of another person) was reported in 1% of patients receiving the 7 mg tablets and 0% of patients receiving the 14 mg tablets or placebo

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It was shown also that BCL-2 gene expression may have a negative prognostic value for some tumors, for example for bladder cancer and hematological malignancies (both lymphoid and myeloid leukemia) [64]