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However, challenges in long-term safety, patient adherence, and clinical practicality limit its widespread adoption

Sermorelin and tesamorelin are GHRH analogs that bind the GHRH receptor, while ipamorelin is a ghrelin mimetic that binds the ghrelin receptor (GHS-R1a)

Side effects are generally mild, but may include temporary scalp redness, dryness, or irritation at the application site

Furthermore, as inflammation plays a vital role in the pathophysiology of insulin resistance and type-two diabetes caused by obesity, the anti-inflammatory effect of the KD is directly related to reducing hepatic steatosis and enhancing overall body glycemic control [35]