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Tehlivets O, et al

doi: 10.1093/toxsci/kfw158 100

Additionally, isotope tracing studies have demonstrated that lactate functions as a major fuel in the TCA cycle, where 13C-lactate labeled TCA intermediates in every tissue of the body, even in tumors (31,32)

Moreover, during this critical ascorbate-glutathione redox recycling reaction, GR significantly accelerates the reduction of the oxidized glutathione (GSSG) to its reduced form glutathione (GSH) to maintain a higher ratio of beneficial GSH relative to GSSG within the chloroplast stroma ( Figure 4 ) Woodson and Chory, 2008)