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Notably, the perinatal lethality observed in Gdf11 -null mice, in contrast to the long-term viability of MSTN-deficient mice, led to complications in characterizing the role of GDF11 in adult tissues and caused many groups to utilize recombinant GDF11 proteins to identify its postnatal function

Systems based on the principle of electrostatic interaction shows remarkable improvement in the cargo capacity, with a 14-fold enhancement in herbicide loading due to the functionalization of trimethylammonium groups (98)

[19] These group-transfer intermediates are called coenzymes