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It has been shown that TRX1 and GPX4 work together to modulate ferroptosis (Bai et al., 2021)

Poulsen HE, Prieme H, Loft S

Zeber-Lubecka N, Ciebiera M, Hennig EE

The chromatin was subsequently immunoprecipitated with specific antibodies (RNA poly II and H3K27ac were positive control, NIgG was the negative control) against the target protein and incubated overnight at 4 C with gentle rotation