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, fluoxetine (78) sertraline (79), promote remission in acute experimental autoimmune encephalomyelitis) BPC 157 affects with region specific influence the brain serotonin synthesis (-[14C]methyl-l-tryptophan autoradiographic measurements) (80), reduces the duration of immobility to a greater extent than imipramine (81)

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The field is promising, but larger controlled human studies are still needed to better define effectiveness, dosing, and long-term safety

According to the revised El Escorial criteria, more than 70% of the ALS cases had a probable or definite diagnosis