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SKU: 41289470292
Price: 24.22 USD
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If we simultaneously inhibited glucose and glutamine oxidation using a cocktail of etomoxir and UK5099, thus requiring cells to use fatty acids, the OCR change in uninfected cells was negligible (Fig

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The underlying mechanism involves AS-IVs ability to reduce mitochondrial ROS in myocardial cells of MI mice, inhibit NLRP3 inflammasome activation, and subsequently downregulate the expression of downstream inflammatory factors such as IL-18 and IL-1, along with the caspase-1 regulator involved in cell pyroptosis