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In summary, we have listed several common microhydrogel delivery systems currently available, including their fabrication methods, their advantages and disadvantages, and the obvious advantages of microspheres for slow long-term drug release compared to microgels

Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: contributions of HO-1 and HO-2 to cytoprotection

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The distance from the blood supply can be up to 8 mm or more ( Under normal physiological conditions, the center of the nucleus pulposus primarily relies on anaerobic glycolysis for metabolism, forming a nutrient gradient from the periphery to the center, characterized by a microenvironment with low glucose (approximately 1 mmol/L) and high lactate (approximately 5 mmol/L) (Urban, 2002)