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Setria is already used in finished supplement products across North America, Europe, Asia, and other global regions where it appears in formulations targeting a broad array of health categories, including healthy aging, detoxification, womens health, and sports nutrition

The above indication was given support when it was shown that injection of free iron directly into the substantia nigra of rodents caused the appearance of Parkinsonian symptoms, which symptoms could be overcome by addition of transferrin, the protein which binds free iron in the blood plasma (Jenner 1994)