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The relationship between these two nutrients is complex and involves a biological process called a redox cycle

Its main structural protein, apolipoprotein (apo) AI, forms the framework that carries phospholipids and cholesterol in HDL ( Clinical studies consistently report lowered HDL-C levels in major depressive disorder (MDD), bipolar disorder (BPD), and schizophrenia, with severity correlating with symptom chronicity and treatment resistance ( Figure 1D )

Compared to oral or injectable forms, cream formulations can reduce the amount of drugs entering the systemic bloodstream, thereby lowering the risk of systemic adverse reactions

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