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The local intestinal immune response not only activates humoral and cellular immunity to recognize foreign pathogens and resist invasive microbial pathogens but also prevents disruption of the commensal gut microbiota ( 1.2 Ischemia reperfusion injury During sepsis, catecholamines are released to redistribute throughout the body to ensure blood supply to the brain, heart, and other important organs

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Arch Biochem Biophys 33:6577 Miller G, Schlauch K, Tam R, Cortes D, Torres MA, Shulaev V, Dangl J, Mittler R (2009) The plant NADPH oxidase RBOHD mediates rapid systemic signaling in response to diverse stimuli