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NOX serves as a prominent source of ROS in the central nervous system, and its isotypes are widely distributed across brain, especially in key structures involved in learning and memory

Figure 4 These molecules could self-react with ROS, but the removal efficiency is higher in enzyme-mediated reactions, like those catalyzed by APX (EC 1.11.1.11), ascorbate oxidase (AscO, EC 1.10.3.3), SOD, catalase (CAT, EC 1.11.1.6), and GPx (EC 1.11.1.9