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8 Recently, several studies have highlighted the potential interest of sirolimus, a mammalian target of rapamycin (mTOR) inhibitor in patients who are refractory or cyclosporine A intolerant

After 72 h, RNA was extracted using an RNeasy Kit (Qiagen, QIA74106) according to the manufacturers instructions

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For example, during strength training and moderate-to-long duration aerobic exercise, there is a substantial increase in the production of pro-inflammatory cytokines, such as interleukin-6 (IL-6) and interleukin-8 (IL-8), as well as the occurrence of oxidative stress [8]