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See FDA warning letters to Jagsonpal Pharmaceuticals Limited (Feb

Sources are drawn from peer-reviewed literature indexed in PubMed and ClinicalTrials.gov

The intensity and duration are central to diagnosis: Mania: Markedly elevated or irritable mood, reduced sleep, risky decisions, significant functional impact Hypomania: Similar but less severe, still noticeable change in behavior Depression: Sustained low mood, fatigue, slowed thinking, reduced functioning Borderline Personality Disorder vs Bipolar Disorder: The Key Differences Episode Duration and Timing A core difference is how long mood and behavior changes typically last

Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease