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Participant groups were equivalent at baseline for all outcome measures

The synergistic effect of alcohol and protein deficiency significantly increases lipid peroxidation products like malondialdehyde (MDA), which aggravates muscle atrophy

After this, acetyl-CoA is ultimately generated into ATP after entering the TCA cycle and OXPHOS [75, 76]

Current diagnostic frameworks such as the DSM-5 and ICD-11 rely predominantly on symptom clusters rather than objective biomarkers, which raises questions about diagnostic precision, cultural applicability, and reliability across settings (Association 2019)