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Mutations in the corresponding GATA-1 gene are linked to many human diseases, including acute megakaryoblastic leukemia in Down Syndrome children (DS-AMKL), X-linked thrombocytopenia, and gray platelet syndrome (6-9)

Drug trials are typically too short to investigate the subject, harmful reactions are selectively reported, and follow-up reporting is underutilized, according to a broad review of these topics published in The International Journal of Risk and Safety in Medicine

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The assay proposed in this manuscript allows large numbers of compounds to be screened, using small amounts of reagents, minimizing handling steps, increasing the overall efficiency of automation