glutathione reductase biosensor Rapid and sensitive electrochemical detection of oxidized form of in whole blood samples using Bi-metallic nanocomposites Real-time monitoring of glutathione in

Then that T4 has to get converted into T3, because T4 is not very active metabolically

NeuroImage (2019) 191:17685

It is well established that T cells shift their metabolism based on their differentiation state and functional capacity: namely, T nave (Tn) and T memory (Tm) cells mainly rely on oxidative phosphorylation (OXPHOS) for their bioenergetic needs, whereas T effector (Te) cells, which are dominantly responsible for tumor killing, are fueled by glycolysis ( Redox metabolism, methionine metabolism, and the general control nonderepressible 2 (GCN2) pathway have all garnered increasing attention in the cancer immunotherapy field as potential therapeutic targets

Int J Mol Sci 14:74057432 Zechmann B, Mller M (2010) Subcellular compartmentation of glutathione in dicotyledonous plants