intracellular glutathione levels Glutathione-mediated nanomedicines for cancer diagnosis and therapy Comparison of intra- and extracellular

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But as the pH rises, the number of negative charges raise due to phosphonate and carboxylate groups ionization ( Figure 2 ) Between pH 2.0 and 5.6, the phosphate acid is deprotonated, resulting in a negative charge allowing the interaction with monovalent cations