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Silymarin is extensively metabolised in the intestines by gut bacteria and may promote wider gastrointestinal health

Generation of Slc25a39 KO and conditional KO mice All animal studies and procedures were conducted according to a protocol approved by the Institutional Animal Care and Use Committee (IACUC) at the Rockefeller University

Representative ChP immunoblots ( c ) and quantification ( d ) of P3 (0-100 M) engagement with KRAS G13D in MDA-MB-231 cells treated with vehicle or STR (250 nM, 3 h)