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HSP40 is a family of chaperones with diverse roles in cancer The HSP40 family, also known as DNAJ proteins, is frequently overexpressed in cancers such as colorectal, gastric, and lung cancers, particularly in cases with lymph node and distant organ metastasis

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However, theoretical concerns exist regarding interference with oxidative mechanisms intended to damage malignant cells

DRD2 agonists, among which cabergoline is the most effective and best tolerated, are first-line therapy for prolactinomas as they are effective in controlling clinical symptoms, PRL levels, and tumor volume ( Figure 1 Somatostatin binds to a family of G-proteins coupled receptors (SSTR1-5), among which subtypes 2 and 5 are expressed at high density in most GH-secreting pituitary tumors ( 2+ and K + channels, all these events being involved in the reduction of hormone secretion [reviewed in Ref