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FavaMTargumSDNierenbergAABleicherLSCarterTAWedelPCet al

R., Athirasala, A., Ji, J., Alvey, C., et al

doi: 10.1371/journal.pone.0132421 36 SteinE

L-Nle was preferred in the N-terminal for optimal inhibition and zinc coordination to the oxygen of the benzamide function is estimated to allow the lipophilic P1 substituent to be easily accommodated in the S1 pocket